Mpox Day 30 – Recent Key Developments

100 Days Mission Mpox Clock: Day 30 (minor update)

The 100 Days Mission (100DM) clock for mpox started on 14th August 2024, following the declaration of mpox a public health emergency of international concern (PHEIC) by WHO. Today we are publishing the Day 30 update on mpox DTV availability. Leading up to Day 100 on 21st November, IPPS will provide updates every 15 days (alternating between major and minor) on the status and progress of mpox DTV availability. The major updates provide detailed deep dives into each tool and highlight specific priority actions to ensure products are available to those who need them. Minor updates like today’s simply track factual changes to the indicators in our tracker. 

These updates are intended to support the work of partners and key initiatives and are developed in consultation with implementing partners of the 100DM. We are open to feedback on the accuracy of our data, please get in touch (info@ippsecretariat.org) if you have information to share. 

Previous updates: 

  • Day 15 update (major update) 

Key Developments

 

Overview: the status of DTVs

 

Diagnostics

 

Therapeutics

 

Vaccines

 

Supporting Resources on Mpox Response 

  • FIND published a protocol for the evaluation of the Mpox diagnostics (POCT and RDTs) 
  • Africa CDC and FIND published recommendations for Mpox Molecular Diagnostic Tests(RT-PCR) 
  • WHO launched a global Strategic Preparedness and Response Plan to stop outbreaks of human-to-human transmission of mpox through coordinated global, regional, and national efforts. 
  • Africa CDC published Mpox Continental Preparedness and Response Plan for Africa 
  • FIND launched a Request for Proposal for mpox diagnostics evaluation and accelerated development in LMICs. 
  • FIND published results from 1st round of evaluations for point-of-care tests – results suggest that POC molecular tests perform better than RDTs.  
  • WHO and partners established an access and allocation mechanism (AAM) for mpox vaccines, treatments, tests